Description

Insulin, Despentapeptide (B26-B30)-Tyrnh2(B25)- is a specifically modified insulin analog, a key intermediate in the research and development of novel insulin-based therapeutics. This compound is crucial for studying the structure-activity relationships of insulin and for the synthesis of insulin derivatives with tailored pharmacokinetic profiles. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies focused on metabolic disorder treatments and peptide hormone engineering.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate for synthesizing novel insulin analogs with modified receptor binding or stability profiles.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the impact of specific peptide chain modifications on insulin's biological activity and metabolic properties.
• Metabolic Disorder Research: A key tool in preclinical studies aimed at developing next-generation treatments for diabetes mellitus.
• Peptide Chemistry & Synthesis: Employed as a building block in advanced solid-phase or solution-phase peptide synthesis for creating hormone derivatives.
• Reference Standard: Can be used as a high-purity chemical reference standard in analytical method development and quality control for insulin-related products.
• Bioconjugation Studies: Acts as a substrate for developing insulin-drug conjugates or other bioconjugates for targeted therapy.

Basic Information

Item	Detail
Product Name	Insulin, Despentapeptide (B26-B30)-Tyrnh2(B25)-
CAS No.	103370-34-9
Molecular Formula	C254H377N65O76S6
Molecular Weight	5808.5 g/mol (approx.)
Synonyms	Despentapeptide(B26-B30) Insulin; [Des-Pentapeptide(B26-B30)]-Insulin; Insulin (B26-B30)-Despentapeptide; Insulin, Des-Pentapeptide (B26-B30); Insulin derivative (103370-34-9); Insulin analog; Modified Insulin Intermediate; Tyr(B25)-NH2 Insulin Derivative
EINECS	Contact for details

Quality Control

Our Insulin, Despentapeptide (B26-B30)-Tyrnh2(B25)- is produced and handled under strict quality management systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccant when not in use. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.