Description

1-Methyl-L-4,5-Dihydroorotic Acid is a specialized derivative of orotic acid, a key intermediate in nucleotide biosynthesis. This high-purity compound is valued for its role as a crucial building block in the research and development of novel pharmaceuticals, particularly in the areas of metabolic and antiviral therapies. It serves as an essential raw material for scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs), especially for metabolic and antiviral drugs.
• Biochemical Research: Used in enzymatic studies and metabolic pathway research related to pyrimidine biosynthesis.
• Nucleotide Analog Synthesis: Serves as a precursor for the development of novel nucleotide analogs with potential therapeutic applications.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Reference Standard: Can be utilized as a certified reference standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	1-Methyl-L-4,5-Dihydroorotic Acid
CAS No.	103365-69-1
Molecular Formula	C6H8N2O4
Molecular Weight	172.14 g/mol
Synonyms	1-Methyl-4,5-dihydro-L-orotic acid; (S)-1-Methyl-4,5-dihydroorotic acid; L-1-Methyl-4,5-dihydroorotic acid; 1-Methyl-L-dihydroorotate; 6-Carboxy-1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine; Methyl dihydroorotate
EINECS	Contact for details

Quality Control

Our 1-Methyl-L-4,5-Dihydroorotic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.