Description

(S)-Benzyl 1-Methyl-2,6-Dioxohexahydropyrimidine-4-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and asymmetric synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• Peptidomimetic Development: Serves as a constrained scaffold in the design and synthesis of peptide analogs and mimetics.
• Academic & Industrial R&D: Utilized in chemical research for developing new synthetic methodologies and exploring novel chemical entities.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke intermediates.

Basic Information

Product Name	(S)-Benzyl 1-Methyl-2,6-Dioxohexahydropyrimidine-4-Carboxylate
CAS No.	103300-85-2
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	(S)-Benzyl 1-Methyl-2,6-dioxohexahydropyrimidine-4-carboxylate; (S)-1-Methyl-2,6-dioxohexahydropyrimidine-4-carboxylic Acid Benzyl Ester; (S)-Benzyl 1-Methyl-2,6-dioxoperhydropyrimidine-4-carboxylate; (S)-Benzyl 1-Methyl-2,6-dioxo-1,3-diazinane-4-carboxylate; (S)-4-(Benzyloxycarbonyl)-1-methyl-2,6-pyrimidinedione; (S)-1-Methyl-2,6-dioxo-1,3-diazinane-4-carboxylic Acid Benzyl Ester; (S)-Benzyl 1-Methyl-2,6-dioxo-1,3-diazinane-4-carboxylate
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 1-Methyl-2,6-Dioxohexahydropyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and pharmaceutical use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.