Description

(S)-Benzyl 2,6-Dioxohexahydropyrimidine-4-Carboxylate is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures with high enantiomeric purity.
• Peptidomimetic Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs for medicinal chemistry applications.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and investigating structure-activity relationships (SAR).

Basic Information

Product Name	(S)-Benzyl 2,6-Dioxohexahydropyrimidine-4-Carboxylate
CAS No.	103300-84-1
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	(S)-Benzyl 2,6-Dioxopiperidine-3-carboxylate; (3S)-1-Benzyl 3-carboxy-2,6-piperidinedione; (S)-1-Benzyl-3-carboxy-2,6-piperidinedione; (S)-1-Carbobenzyloxy-5-oxopiperidine-2-carboxylic Acid; (S)-N-Cbz-5-oxopipecolic Acid; (S)-1-[(Benzyloxy)carbonyl]-5-oxopiperidine-2-carboxylic Acid; (S)-5-Oxo-1-[(phenylmethoxy)carbonyl]piperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2,6-Dioxohexahydropyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.