Description

4-Methyl-2-Phenyl-5-Pyrimidinecarboxylic Acid is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyrimidine core for biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a potential electron-transport or host material in the development of organic electronic materials.
• Ligand and Catalyst Development: The carboxylic acid functionality allows for coordination to metals, making it useful in creating novel ligands for catalytic systems.
• Chemical Research & Development: A versatile building block for academic and industrial research in heterocyclic and medicinal chemistry.
• Material Science: Investigated for use in the synthesis of specialty polymers and advanced functional materials.

Basic Information

Product Name	4-Methyl-2-Phenyl-5-Pyrimidinecarboxylic Acid
CAS No.	103249-79-2
Molecular Formula	C12H10N2O2
Molecular Weight	214.22 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 4-methyl-2-phenyl-; 2-Phenyl-4-methyl-5-pyrimidinecarboxylic acid; 4-Methyl-2-phenylpyrimidine-5-carboxylic acid; NSC 405124; 4-Methyl-2-phenyl-5-carboxypyrimidine; 2-Phenyl-4-methylpyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Phenyl-5-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.