Description

Igf-Ii (33-40) CAS NO 103244-41-3 is a synthetic peptide fragment derived from Insulin-like Growth Factor II (IGF-II), representing the amino acid sequence from positions 33 to 40. This specific fragment is a crucial research-grade biochemical tool for studying the structure-activity relationships and biological functions of IGF-II. It is primarily utilized by research institutions and pharmaceutical development companies engaged in endocrinology, oncology, and metabolic disease research. The compound is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a reference standard and active probe in studies investigating the mechanism of action of IGF-II and its receptor interactions.
• Pharmaceutical Development: Serves as a key intermediate or starting material in the research and development of peptide-based therapeutics targeting growth factor pathways.
• Cell Culture Studies: Applied in in vitro assays to examine the effects of specific IGF-II domains on cell proliferation, differentiation, and apoptosis.
• Antibody Production: Utilized as an antigen for the generation and characterization of specific antibodies against the IGF-II (33-40) epitope.
• Signal Transduction Analysis: Aids in mapping and understanding the downstream signaling cascades activated by specific regions of the IGF-II molecule.
• Competitive Binding Assays: Employed in receptor-ligand binding studies to determine binding affinities and specificities.

Basic Information

Product Name	Igf-Ii (33-40)
CAS No.	103244-41-3
Molecular Formula	C38H62N12O12
Molecular Weight	854.97 g/mol
Synonyms	IGF-II (33-40); Insulin-like growth factor II (33-40); IGF-2 (33-40); IGF-II fragment (33-40); H-Tyr-Leu-Leu-Ala-Ala-Leu-Leu-Gly-OH; Tyr-Leu-Leu-Ala-Ala-Leu-Leu-Gly; YLLAA LLG; (33-40)-IGF-II
EINECS	Contact for details

Quality Control

Our Igf-Ii (33-40) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Quality is verified by multiple orthogonal methods including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each batch to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.