Description

(3,5-Diiodo-Tyr1)-Dtlet is a specialized, iodine-modified tyrosine derivative peptide. This compound is a critical building block in advanced peptide synthesis and biochemical research, offering precise structural control. It is primarily utilized by pharmaceutical researchers, peptide manufacturers, and academic institutions developing novel therapeutic agents and diagnostic tools.

Application

• Peptide Synthesis: A key intermediate for constructing complex peptides with site-specific iodine labeling for structure-activity relationship (SAR) studies.
• Radiopharmaceutical Precursor: Serves as a precursor molecule for the development of iodine-123 or iodine-131 labeled compounds used in diagnostic imaging and targeted radiotherapy.
• Biochemical Research: Used as a molecular probe to study enzyme-substrate interactions, receptor binding, and protein folding mechanisms.
• Pharmaceutical Development: Integral in the research and development of novel peptide-based drugs targeting metabolic disorders and hormonal pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in peptide analysis.

Basic Information

Product Name	(3,5-Diiodo-Tyr1)-Dtlet
CAS No.	103213-63-4
Molecular Formula	C17H24I2N4O5
Molecular Weight	634.20 g/mol
Synonyms	3,5-Diiodo-L-tyrosyl-D-threonyl-L-leucyl-L-threonine; H-D-Iodotyrosine-Thr-Leu-Thr-OH; (3,5-Diiodotyrosine)1-Threonyl-Leucyl-Threonine; DTlet derivative; Iodinated tyrosine peptide; 3,5-Diiodo-Tyr-Thr-Leu-Thr; L-Threonine, L-leucyl-L-threonyl-3,5-diiodo-L-tyrosyl-
EINECS	Contact for details

Quality Control

Every batch of (3,5-Diiodo-Tyr1)-Dtlet is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research requirements. A detailed Certificate of Analysis (COA) including HPLC purity, chiral purity, and residual solvent analysis is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.