Description

o-Nitrophenylsulfenyl-Lysyl-Tryptophan is a specialized, protected tripeptide derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D for drug discovery, particularly in the synthesis of novel therapeutic agents targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of complex peptide-based drugs and bioactive molecules.
• Peptidomimetic Research: Serves as a crucial scaffold for designing and synthesizing peptidomimetics with enhanced stability and bioavailability.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive sulfenyl group.
• Protease Inhibitor Development: Employed in the research and synthesis of potential protease inhibitors for treating viral infections and other conditions.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes to study enzyme function and mechanism.
• Academic & Industrial R&D: A valuable reagent for research institutions and chemical companies exploring new synthetic methodologies and novel therapeutic entities.

Basic Information

Product Name	o-Nitrophenylsulfenyl-Lysyl-Tryptophan
CAS No.	103088-69-3
Molecular Formula	C24H28N6O6S
Molecular Weight	528.58 g/mol
Synonyms	Nε-(2-Nitrophenylsulfenyl)-L-lysyl-L-tryptophan; Nε-o-Nitrophenylsulfenyl-L-lysyl-L-tryptophan; o-NPS-Lys-Trp; Lys(Nps)-Trp; NPS-Lys-Trp-OH; 2-Nitrophenylsulfenyl-L-lysyl-L-tryptophan; L-Tryptophan, N2-[N6-[(2-nitrophenyl)thio]-L-lysyl]-
EINECS	Contact for details

Quality Control

Our o-Nitrophenylsulfenyl-Lysyl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.