Description

2-Pyrimidinamine, 4-Ethynyl-6-Methyl- (9Ci) is a specialized heterocyclic building block featuring a pyrimidine core functionalized with an ethynyl group. This compound is valued for its role as a key synthetic intermediate in advanced organic and medicinal chemistry, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. The unique reactivity of the ethynyl moiety makes it a versatile handle for click chemistry and other coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology: Employed in probe and linker synthesis for studying biological systems and target identification.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development and novel compound library synthesis.

Basic Information

Product Name	2-Pyrimidinamine, 4-Ethynyl-6-Methyl- (9Ci)
CAS No.	103011-51-4
Molecular Formula	C7H7N3
Molecular Weight	133.15 g/mol
Synonyms	4-Ethynyl-6-methylpyrimidin-2-amine; 4-Ethynyl-6-methyl-2-pyrimidinamine; 6-Methyl-4-ethynyl-2-pyrimidinamine; 2-Amino-4-ethynyl-6-methylpyrimidine; 4-Ethynyl-6-methyl-2-aminopyrimidine; 103011-51-4
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 4-Ethynyl-6-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its easily oxidized nature, prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.