Description

Atrial Natriuretic Factor, Des-Ser(5)-Ser(6)- is a synthetic peptide analog of the endogenous atrial natriuretic peptide (ANP), a key hormone involved in cardiovascular homeostasis. This compound is of significant value for research and development due to its specific biological activity, primarily in modulating blood pressure and electrolyte balance. It is essential for pharmaceutical researchers, academic institutions, and diagnostic developers focused on cardiovascular disease, renal function, and natriuretic peptide receptor studies.

Application

• Cardiovascular Research: Used as a reference standard and active agent in studies investigating hypertension, heart failure, and vascular biology.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (e.g., ELISA, RIA) for ANP detection.
• Receptor Binding Studies: Employed in competitive binding assays to study the affinity and function of natriuretic peptide receptors (NPR-A, NPR-B).
• Pharmaceutical R&D: Acts as a lead compound or intermediate in the discovery and development of novel therapeutic agents targeting the natriuretic peptide system.
• Academic & Clinical Studies: Utilized in physiological experiments to understand the role of ANP in renal sodium excretion and fluid balance.
• Diagnostic Manufacturing: Used as a calibrator or quality control material in the production of in-vitro diagnostic kits for cardiovascular biomarkers.

Basic Information

Product Name	Atrial Natriuretic Factor, Des-Ser(5)-Ser(6)-
CAS No.	102910-11-2
Molecular Formula	C106H174N34O31S2
Molecular Weight	~2410.8 g/mol
Synonyms	ANF (5-28) (human, rat); Atriopeptin 28 (5-28); ANP (5-28); Des-Ser5-Ser6-Atrial Natriuretic Peptide (5-28); Atrial Natriuretic Peptide Fragment 5-28; Cardionatrin I (5-28); hANP (5-28); rANP (5-28)
EINECS	Contact for details

Quality Control

Our Atrial Natriuretic Factor, Des-Ser(5)-Ser(6)- is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and Mass Spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.