Description

Dnpyr-Dl-Tryptophan CAS NO 102850-24-8 is a protected derivative of the essential amino acid tryptophan, featuring a dinitropyrene (Dnpyr) group. This specialized compound is critical for advanced peptide synthesis and biochemical research, where it serves as a key building block to introduce tryptophan residues under controlled conditions. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the development of novel peptides, peptidomimetics, and proteomics studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A crucial protected amino acid for the controlled incorporation of tryptophan into peptide chains, preventing unwanted side reactions.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, hormone analogs, and other bioactive molecules.
• Biochemical Studies: Employed in proteomics and enzyme-substrate interaction studies to investigate protein structure and function.
• Peptidomimetic Design: Serves as a starting material for creating modified peptides with enhanced stability or biological activity.
• Organic Synthesis Intermediates: Acts as a chiral synthon for the preparation of more complex, non-proteinogenic amino acids and fine chemicals.

Basic Information

Product Name	Dnpyr-Dl-Tryptophan
CAS No.	102850-24-8
Molecular Formula	C21H20N4O4
Molecular Weight	392.41 g/mol
Synonyms	N-[(2,4-Dinitrophenyl)sulfonyl]-DL-tryptophan; Dnpyr-DL-Trp; Dnpyr-DL-Tryptophan; 2,4-Dinitrobenzenesulfonyl-DL-tryptophan; (RS)-2-Amino-3-(1H-indol-3-yl)propanoic acid N-(2,4-dinitrophenyl)sulfonyl derivative; DL-Tryptophan, N-[(2,4-dinitrophenyl)sulfonyl]-; Dnpyr protected DL-tryptophan
EINECS	Contact for details

Quality Control

Our Dnpyr-Dl-Tryptophan is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.