Description

Angiotensinogen Fragment 11-14 is a defined tetrapeptide sequence derived from the angiotensinogen protein, a key component of the renin-angiotensin system (RAS). This high-purity peptide fragment is essential for biochemical research, serving as a critical reference standard and substrate in enzymatic studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers focused on cardiovascular and renal system research, hypertension studies, and novel drug discovery.

Application

• Biochemical Research: Used as a specific substrate or reference compound in studies of renin and other proteolytic enzymes within the RAS pathway.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the development of drugs targeting hypertension, heart failure, and kidney diseases.
• Diagnostic Assays: Employed in the calibration and development of immunoassays and enzymatic assays designed to measure components of the renin-angiotensin system.
• Academic Studies: Facilitates fundamental research into the structure, function, and metabolism of angiotensinogen and its bioactive peptide fragments.
• Peptide Synthesis Reference: Acts as a purity benchmark and control in the synthesis of longer angiotensinogen-related peptide sequences.

Basic Information

Product Name	Angiotensinogen Fragment 11-14
CAS No.	102813-98-9
Molecular Formula	C19H32N6O6
Molecular Weight	440.50 g/mol
Synonyms	Angiotensinogen (11-14); L-Leucyl-L-valyl-L-tyrosyl-L-serine; Leu-Val-Tyr-Ser; LVYS; H-Leu-Val-Tyr-Ser-OH; Tetrapeptide LVYS; Angiotensinogen Tetrapeptide Fragment
EINECS	Contact for details

Quality Control

Our Angiotensinogen Fragment 11-14 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.