Description

2,4-Diamino-6-Hydroxypyrimidine Hemisulfate is a high-purity pyrimidine derivative salt, a key building block in organic synthesis. This compound is valued for its role as a versatile intermediate in the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), nucleoside analogs, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Agrochemical Synthesis: Used in the development of herbicides and plant growth regulators based on pyrimidine chemistry.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty organic compounds.
• Academic & Industrial R&D: A fundamental building block for novel heterocyclic compound libraries in medicinal chemistry.

Basic Information

Product Name	2,4-Diamino-6-Hydroxypyrimidine Hemisulfate
CAS No.	102783-80-2
Molecular Formula	C4H6N4O · ½H2SO4
Molecular Weight	176.14 g/mol (Free base: 126.12)
Synonyms	2,6-Diamino-4-hydroxypyrimidine hemisulfate; 4-Hydroxy-2,6-diaminopyrimidine hemisulfate; 6-Hydroxy-2,4-diaminopyrimidine sulfate (1:0.5); Dihydroxypyrimidine hemisulfate; Pyrimidine-2,4-diamine, 6-hydroxy-, sulfate (1:0.5); Isobarbituric acid diamine hemisulfate
EINECS	Contact for details

Quality Control

Our 2,4-Diamino-6-Hydroxypyrimidine Hemisulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.