Description

4,5-Diamino-6-Hydroxypyrimidine Hemisulfate is a high-purity pyrimidine derivative salt, serving as a critical pharmaceutical intermediate and building block in organic synthesis. Its value lies in its role as a precursor for the synthesis of complex heterocyclic compounds, including purine analogs and nucleoside derivatives. This product is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral and anticancer agents, particularly purine-based nucleoside analogs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for creating complex heterocyclic structures in specialty chemistry.
• Biochemical Research: Utilized in nucleotide chemistry and as a substrate for enzymatic studies.
• Material Science: Investigated for potential use in the development of organic electronic materials and ligands for metal complexes.

Basic Information

Product Name	4,5-Diamino-6-Hydroxypyrimidine Hemisulfate
CAS No.	102783-18-6
Molecular Formula	C4H7N4O · ½H2SO4
Molecular Weight	182.14 g/mol (for hemisulfate salt)
Synonyms	4,5-Diamino-6-hydroxypyrimidine sulfate (1:0.5); 6-Hydroxy-4,5-diaminopyrimidine hemisulfate; 4,5-Diamino-6(1H)-pyrimidinone hemisulfate; 4,5-Diamino-6-pyrimidinol hemisulfate; DAHP Hemisulfate; 2,4-Diamino-5-hydroxy-6-pyrimidinyl sulfate
EINECS	Contact for details

Quality Control

Our 4,5-Diamino-6-Hydroxypyrimidine Hemisulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.