Description

Atrial Natriuretic Factor (3-28) (Human) is a bioactive peptide fragment derived from the human atrial natriuretic peptide (ANP) hormone. This specific sequence is critical for cardiovascular research and pharmaceutical development, as it retains significant biological activity related to natriuresis, diuresis, and vasodilation. It is an essential reference standard and raw material for researchers and manufacturers in the fields of cardiovascular drug discovery, diagnostic assay development, and biochemical research. The compound is supplied with high purity to ensure reliable and reproducible experimental and production outcomes.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in drug development and quality control.
• Biochemical Research: Serves as a key reagent in studies investigating the ANP signaling pathway, receptor binding assays, and mechanisms of blood pressure regulation.
• Diagnostic Kit Production: Employed as a critical antigen or calibrator in the manufacture of immunoassay kits for measuring ANP levels in clinical samples.
• Peptide Drug Synthesis: Acts as an intermediate or active pharmaceutical ingredient (API) in the development of novel cardiovascular therapeutics.
• Academic & Institutional Research: Utilized in university and hospital laboratories for fundamental physiological and pharmacological studies.

Basic Information

Product Name	Atrial Natriuretic Factor (3-28) (Human)
CAS No.	102686-43-1
Molecular Formula	C119H190N40O39S2
Molecular Weight	2741.1 g/mol
Synonyms	ANF (3-28), human; Atrial Natriuretic Peptide (3-28); ANP (3-28); Cardionatrin (3-28); Atriopeptin (3-28); hANP (3-28); Ser103-Tyr126 Atrial Natriuretic Factor (Human); 102686-43-1
EINECS	Contact for details

Quality Control

Every batch of Atrial Natriuretic Factor (3-28) (Human) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with high-purity peptide standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.