Description

2-Bromo-5-(Trifluoromethyl)Benzaldehyde is a versatile and high-value aromatic aldehyde building block, distinguished by its bromine and trifluoromethyl substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic display and lighting materials.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fine Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating functional molecules.

Basic Information

Product Name	2-Bromo-5-(Trifluoromethyl)Benzaldehyde
CAS No.	102684-91-3
Molecular Formula	C8H4BrF3O
Molecular Weight	253.02 g/mol
Synonyms	5-(Trifluoromethyl)-2-bromobenzaldehyde; 2-Bromo-α,α,α-trifluoro-m-tolualdehyde; m-Trifluoromethyl-2-bromobenzaldehyde; Benzaldehyde, 2-bromo-5-(trifluoromethyl)-; 2-Bromo-5-trifluoromethylbenzaldehyde; 2-Bromo-α,α,α-trifluoro-3-formyltoluene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.