Description

3-[(3-Chloro-4-Methoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in antiviral and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for the development of proprietary APIs targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or reagent in biochemical assays and pharmacological studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, fluorinated heterocyclic compounds.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	3-[(3-Chloro-4-Methoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione
CAS No.	102613-23-0
Molecular Formula	C₁₂H₁₀ClFN₂O₃
Molecular Weight	284.67 g/mol
Synonyms	5-Fluoro-3-[(3-chloro-4-methoxyphenyl)methyl]-1H-pyrimidine-2,4-dione; 3-[(3-Chloro-4-methoxyphenyl)methyl]-5-fluorouracil; 5-Fluoro-3-(3-chloro-4-methoxybenzyl)uracil; 102613-23-0; Fluorinated uracil derivative; Chloromethoxybenzyl fluorouracil
EINECS	Contact for details

Quality Control

Our production of 3-[(3-Chloro-4-Methoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored in a dark place to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.