Description

3-[(3-Chloro-4-Ethoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione is a high-purity, fluorinated pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure imparts specific biological activity and metabolic stability. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel antiviral, anticancer, or anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used as a precursor in the development of next-generation herbicides, fungicides, or insecticides with enhanced efficacy.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Reference Standard: Utilized as an analytical standard for quality control and regulatory submissions in API production.

Basic Information

Product Name	3-[(3-Chloro-4-Ethoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione
CAS No.	102613-21-8
Molecular Formula	C13H12ClFN2O3
Molecular Weight	298.70 g/mol
Synonyms	5-Fluoro-3-[(3-chloro-4-ethoxyphenyl)methyl]pyrimidine-2,4(1H,3H)-dione; 3-[(3-Chloro-4-ethoxybenzyl)]-5-fluorouracil; 5-Fluoro-1H-pyrimidine-2,4-dione, 3-[(3-chloro-4-ethoxyphenyl)methyl]-; 102613-21-8; 3-(3-Chloro-4-ethoxybenzyl)-5-fluorouracil; Fluorinated pyrimidine derivative; Chloroethoxybenzyl fluorouracil
EINECS	Contact for details

Quality Control

Our 3-[(3-Chloro-4-Ethoxy-Phenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.