Description

Z-β-Ala-Gly-Gly-Oh is a synthetic tripeptide derivative featuring a Z-protected β-alanine residue. This compound serves as a crucial building block in peptide synthesis and medicinal chemistry research, offering a protected amine group for controlled chain elongation. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic peptides and studying enzyme-substrate interactions.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of complex peptide-based drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for proteases and peptidases, to investigate catalytic mechanisms.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening against biological targets.
• Prodrug Development: Employed in the design of peptide prodrugs to enhance the bioavailability and targeted delivery of active pharmaceutical ingredients.
• Material Science: Potential monomer for creating novel bio-inspired polymers and hydrogels with specific degradation or cell-adhesion properties.

Basic Information

Product Name	Z-β-Ala-Gly-Gly-Oh
CAS No.	102601-37-6
Molecular Formula	C15H19N3O6
Molecular Weight	337.33 g/mol
Synonyms	N-Carbobenzoxy-β-alanylglycylglycine; Z-β-Ala-Gly-Gly-OH; Benzyloxycarbonyl-β-alanyl-glycyl-glycine; CBZ-β-Ala-Gly-Gly; Nα-[(Benzyloxy)carbonyl]-β-alanylglycylglycine; (Benzyloxy)carbonyl-β-alanyl-glycyl-glycine; Z-β-Ala-Gly-Gly; N-CBZ-β-alanyl-glycyl-glycine
EINECS	Contact for details

Quality Control

Our Z-β-Ala-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.