Description

Desacetylthymosin Alpha(11) is a synthetic peptide fragment derived from thymosin α-1, a naturally occurring immunomodulatory polypeptide. This compound is of significant interest in advanced pharmaceutical research and development due to its role in studying immune system regulation and T-cell function. It serves as a critical intermediate and reference standard for researchers and manufacturers in the fields of immunology, oncology, and peptide-based therapeutics. The product is supplied as a high-purity material to ensure reliable and reproducible experimental and production outcomes.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis and study of thymosin α-1 and related immunomodulatory peptides.
• Reference Standard: Used for quality control, method development, and calibration in analytical laboratories (HPLC, MS).
• Biochemical Studies: Investigation of mechanisms related to T-cell differentiation, maturation, and immune response modulation.
• Preclinical Development: Evaluation in animal models for potential therapeutic applications in immune disorders and cancer.
• Peptide Library Synthesis: Serves as a building block for creating specialized peptide libraries for screening purposes.
• API Manufacturing: Potential use as a starting material or intermediate in the Good Manufacturing Practice (GMP) production of therapeutic peptides.

Basic Information

Product Name	Desacetylthymosin Alpha(11)
CAS No.	102272-19-5
Molecular Formula	C129H215N33O55
Molecular Weight	2848.3 g/mol (approximate)
Synonyms	Desacetyl Thymosin α(11); Thymosin α-1 Fragment (1-11); N-Acetyl-less Thymosin Alpha(11); Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-OH; Tα1(1-11); Immunomodulatory Peptide Fragment; L-Seryl-L-α-aspartyl-L-α-alanyl-L-α-alanyl-L-α-valyl-L-α-aspartyl-L-α-threonyl-L-α-seryl-L-α-seryl-L-α-glutamyl-L-α-isoleucyl-L-α-threonine
EINECS	Contact for details

Quality Control

Every batch of Desacetylthymosin Alpha(11) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for HPLC purity, peptide content, amino acid analysis, and mass spectrometry confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.