Description

Z-Tyr(3,5-I2)-Oet is a specialized, iodine-substituted tyrosine derivative protected with a benzyloxycarbonyl (Z) group and esterified with an ethoxy (Oet) moiety. This compound serves as a critical protected amino acid building block for solid-phase peptide synthesis (SPPS) and other advanced organic syntheses. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel peptide-based therapeutics and biochemical probes.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for the controlled incorporation of iodinated tyrosine residues into custom peptide sequences.
• Pharmaceutical Research: Used in the development and production of peptide hormones, enzyme inhibitors, and receptor-targeting agents where iodine atoms serve as handles for radiolabeling or structural modification.
• Bioconjugation & Probe Development: The iodine substituents provide sites for further functionalization, making it valuable for creating fluorescent tags, affinity labels, and other biochemical probes.
• Academic & Industrial R&D: Employed in chemical biology studies to investigate protein-protein interactions, enzyme mechanisms, and signal transduction pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in peptide chemistry laboratories.

Basic Information

Product Name	Z-Tyr(3,5-I2)-Oet
CAS No.	102202-92-6
Molecular Formula	C19H19I2NO5
Molecular Weight	619.17 g/mol
Synonyms	N-Carbobenzoxy-3,5-diiodo-L-tyrosine ethyl ester; Z-3,5-Diiodo-L-tyrosine ethyl ester; Nα-Z-3,5-Diiodo-L-tyrosine ethyl ester; Benzyloxycarbonyl-3,5-diiodotyrosine ethyl ester; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(3,5-diiodo-4-hydroxyphenyl)propanoic acid ethyl ester; Z-Diiodotyrosine-OEt; Z-L-Tyr(3,5-I2)-OEt
EINECS	Contact for details

Quality Control

Our Z-Tyr(3,5-I2)-Oet is manufactured under strict quality protocols to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and spectroscopic identification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.