Description

4-Fluorothreonine is a fluorinated derivative of the essential amino acid threonine, offering unique biochemical properties for advanced research and synthesis. This compound is a valuable chiral building block and a key intermediate in the development of novel pharmaceuticals, agrochemicals, and biochemical probes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries for drug discovery, metabolic studies, and the synthesis of fluorinated bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of fluorinated drugs, including antibiotics and enzyme inhibitors.
• Biochemical Research: Used as a substrate analog in metabolic pathway studies and enzyme mechanism investigations to understand biological processes.
• Agrochemical Synthesis: Serves as a key precursor in the creation of novel, fluorinated pesticides and herbicides with enhanced activity and stability.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships (SAR) and to modulate peptide stability and bioavailability.
• Proteomics & Labeling: Potential use in the design of chemical probes for labeling and tracking proteins within biological systems.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	4-Fluorothreonine
CAS No.	102130-93-8
Molecular Formula	C4H8FNO3
Molecular Weight	137.11 g/mol
Synonyms	(2S,3S)-2-Amino-3-fluoro-4-hydroxybutanoic acid; (2S,3S)-4-Fluorothreonine; L-4-Fluorothreonine; 3-Fluoro-L-threonine; 4-Fluoro-L-threonine; 4-Fluoro-threonine; 4-FT; FLT
EINECS	Contact for details

Quality Control

Our 4-Fluorothreonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.