Description

(D-Ala2,Hyp4,Tyr5)-β-Casomorphin (1-5) Amide Acetate Salt is a synthetic, modified peptide analog of β-casomorphin, a bioactive fragment derived from bovine milk casein. This compound is of significant interest for its potential role in modulating opioid receptor activity and serves as a critical research tool in neuropharmacology and peptide biochemistry. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the study of pain management, gastrointestinal function, and central nervous system disorders.

Application

• Biomedical Research: As a reference standard and active agent in studies investigating opioid receptor (MOR) binding affinity, selectivity, and signal transduction pathways.
• Pharmacological Assay Development: Used in the development and validation of in vitro and in vivo assays for screening novel analgesic or therapeutic compounds.
• Neuroscience Studies: Employed to explore the physiological and behavioral effects of casomorphin peptides, including their potential roles in stress response and mood regulation.
• Peptide Chemistry & Drug Discovery: Serves as a key intermediate or template for the design and synthesis of new peptide-based pharmaceuticals with improved stability or efficacy.
• Academic Research: Utilized in university laboratories for fundamental research into the structure-activity relationships (SAR) of opioid peptides.

Basic Information

Product Name	(D-Ala2,Hyp4,Tyr5)-β-Casomorphin (1-5) Amide Acetate Salt
CAS No.	102029-98-1
Molecular Formula	C33H46N8O10 • xC2H4O2
Molecular Weight	714.78 g/mol (Free base)
Synonyms	H-Tyr-D-Ala-Phe-Hyp-Gly-NH2 acetate salt; β-Casomorphin (1-5), (D-Ala2,Hyp4,Tyr5)-, amide, acetate; D-Ala2, Hyp4, Tyr5-β-Casomorphin (1-5) amide; Modified β-Casomorphin-5 amide; Opioid peptide fragment analog; [D-Ala2, trans-4-Hydroxy-L-proline4, Tyr5]-β-Casomorphin (1-5) amide acetate; Tyr-D-Ala-Phe-Hyp-Gly-NH2 • AcOH
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and content. We adhere to GMP principles for the handling of research-grade bioactive peptides to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Content)	≥ 97.0% (on anhydrous, solvent-free basis)
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	1.0 - 3.0 eq
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.