Description

H-Ala-Nh2 HBr is a high-purity, protected amino acid derivative, specifically the hydrobromide salt of L-alaninamide. This compound serves as a critical building block (synthon) in the synthesis of complex peptides, pharmaceuticals, and bioactive molecules. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used as a protected amino acid component in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Research: Serves as a substrate or precursor in enzymatic studies and metabolic pathway research.
• Fine Chemical Synthesis: Building block for creating specialized organic compounds, including catalysts and ligands.
• Cosmetic Peptides: Potential ingredient in the synthesis of peptides for advanced skincare formulations.

Basic Information

Product Name	H-Ala-Nh2 HBr
CAS No.	102029-80-1
Molecular Formula	C₃H₉N₂O•HBr
Molecular Weight	185.03 g/mol
Synonyms	L-Alaninamide, hydrobromide; H-Ala-NH2•HBr; (S)-2-Aminopropanamide hydrobromide; Alaninamide HBr; 2-Aminopropionamide hydrobromide; L-2-Aminopropionamide hydrobromide; H-L-Ala-NH2•HBr; NSC 334905
EINECS	Contact for details

Quality Control

Our H-Ala-Nh2 HBr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	+7.0° to +9.0° (c=1 in H₂O)
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.