Description

Ac-Ala-Ala-Pro-Ala-Betana CAS NO 102029-65-2 is a synthetic, sequence-specific peptide substrate designed for biochemical research and diagnostic applications. This compound is of significant value for studying enzyme kinetics and activity, particularly for proteases like elastase, due to its precise amino acid sequence. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on enzymology and biomarker discovery.

Application

• Protease/Elastase Substrate: Used as a specific chromogenic or fluorogenic substrate for the kinetic analysis and quantification of elastase and related serine protease activity.
• Biochemical Research: Essential tool in enzymology studies to investigate enzyme mechanisms, inhibition, and substrate specificity under controlled laboratory conditions.
• Diagnostic Assay Development: Serves as a key component in the development of in vitro diagnostic (IVD) tests for conditions involving dysregulated protease activity.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitor candidates for therapeutic development.
• Quality Control in Biologics: Can be utilized to monitor the presence and activity of specific proteases during the production and purification of biopharmaceuticals.

Basic Information

Product Name	Ac-Ala-Ala-Pro-Ala-Betana
CAS No.	102029-65-2
Molecular Formula	C24H38N6O8
Molecular Weight	538.60 g/mol
Synonyms	N-Acetyl-Ala-Ala-Pro-Ala-4-Nitroanilide; Ac-AAPAna; Acetyl-Alanyl-Alanyl-Prolyl-Alanyl-4-Nitroanilide; N-Acetyl-L-alanyl-L-alanyl-L-prolyl-L-alanine 4-nitroanilide; Acetyl-AAPAna; Elastase Substrate IV; Suc-AAPF-pNA (structurally related analog); Alanine Alanine Proline Alanine Betana
EINECS	Contact for details

Quality Control

Our Ac-Ala-Ala-Pro-Ala-Betana is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.