Description

Bz-Phe-Val-Arg-4M-β-Na Hcl is a specialized peptide derivative used as a chromogenic substrate for serine proteases. This compound matters for its high specificity and sensitivity in enzymatic assays, enabling precise biochemical research and diagnostic development. It is primarily needed by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic research institutions focused on protease activity and inhibitor screening.

Application

• Biochemical Research: As a chromogenic substrate for the kinetic study and characterization of serine proteases like thrombin, trypsin, and related enzymes.
• Diagnostic Assay Development: Used in the formulation of colorimetric test kits for clinical diagnostics, particularly for coagulation factor and protease activity tests.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential protease inhibitor drug candidates.
• Enzyme Activity Monitoring: For real-time, quantitative measurement of protease activity in complex biological samples during purification or analysis.
• Quality Control in Biologics: Used to assess the potency and consistency of enzyme-based therapeutic products during manufacturing.

Basic Information

Product Name	Bz-Phe-Val-Arg-4M-β-Na Hcl
CAS No.	102029-41-4
Molecular Formula	C34H45N8O6Cl
Molecular Weight	697.22 g/mol
Synonyms	Benzoyl-Phe-Val-Arg-4-Methoxy-β-Naphthylamide Hydrochloride; Bz-Phe-Val-Arg-4MeO-βNA HCl; Chromogenic Substrate for Serine Proteases; Bz-F-V-R-4M-β-NA HCl; Nα-Benzoyl-L-phenylalanyl-L-valyl-L-arginine 4-methoxy-β-naphthylamide hydrochloride; Thrombin Chromogenic Substrate; Serine Protease Substrate 102029-41-4
EINECS	Contact for details

Quality Control

Our Bz-Phe-Val-Arg-4M-β-Na Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Clear, colorless solution in DMSO or DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.