Description

Cholecystokinin 21 CAS NO 101831-07-6 is a bioactive peptide fragment derived from the larger cholecystokinin (CCK) hormone, specifically representing the C-terminal 21 amino acid sequence. This compound is of significant value in biochemical and pharmacological research due to its role in studying digestive processes, satiety signaling, and neurological functions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on gastrointestinal and central nervous system disorders.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating the structure-activity relationship of cholecystokinin and its receptor interactions.
• Pharmacological Assays: Employed in in vitro and in vivo assays to screen for potential agonists or antagonists targeting CCK receptors for therapeutic development.
• Diagnostic Development: Serves as a critical component in the development of immunoassays and diagnostic kits for measuring CCK levels in biological samples.
• Neuroscience Studies: Applied in research exploring the role of CCK in anxiety, panic disorders, and memory processes within the brain.
• Gastrointestinal Physiology: Used to study the hormone's effects on pancreatic enzyme secretion, gallbladder contraction, and gut motility.

Basic Information

Product Name	Cholecystokinin 21
CAS No.	101831-07-6
Molecular Formula	C129H202N34O39S2
Molecular Weight	Approx. 2859.3 g/mol
Synonyms	CCK-21; Cholecystokinin (21-33); CCK (21-33); Sincalide fragment (21-33); CCK-21 Peptide; Cholecystokinin C-terminal 21-peptide; CCK-21 (human); H-Arg-Ile-Ser-Asp-Arg-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
EINECS	Contact for details

Quality Control

Our Cholecystokinin 21 is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.