Description

5-Iodo-2-Methoxypyrimidine is a versatile halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its iodine substituent, which offers excellent reactivity for cross-coupling reactions, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Biology: Serves as a probe or labeling agent in biochemical research due to the iodine moiety.
• Ligand and Catalyst Development: Intermediate for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	5-Iodo-2-Methoxypyrimidine
CAS No.	101803-06-9
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	2-Methoxy-5-iodopyrimidine; 5-Iodo-2-methoxypyrimidine; 5-Iodo-2-pyrimidinyl methyl ether; 2-Pyrimidinyl methyl ether, 5-iodo-; 5-Iodo-2-methoxy-pyrimidine; 5-Iodo-2-methoxy-1,3-diazine
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.