Description

n-2-(Hydroxyethyl)-L-Valine is a specialized amino acid derivative, specifically an L-valine molecule modified with a hydroxyethyl group on the nitrogen. This structural modification imparts unique physicochemical properties, making it a valuable chiral building block and intermediate in advanced synthesis. It is primarily utilized in the research and development of novel pharmaceuticals, particularly in the synthesis of peptide-based drugs and complex active pharmaceutical ingredients (APIs). Industries requiring high-purity, custom chiral intermediates for life science applications will find this compound essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-mimetic drugs and complex Active Pharmaceutical Ingredients (APIs).
• Peptide Chemistry: Used as a modified amino acid building block in solid-phase and solution-phase peptide synthesis to introduce specific functional groups.
• Proteomics Research: Serves as a reagent or standard in biochemical research for studying protein structure and function.
• Ligand Synthesis: Employed in the development of specialized chelating agents or ligands for catalytic and diagnostic applications.
• Bioconjugation: The hydroxyethyl group provides a handle for further chemical modification, useful in creating antibody-drug conjugates (ADCs) or labeled biomolecules.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective organic synthesis to control the configuration of new chiral centers.

Basic Information

Product Name	n-2-(Hydroxyethyl)-L-Valine
CAS No.	101769-73-7
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	L-Valine, N-(2-hydroxyethyl)-; N-(2-Hydroxyethyl)valine; 2-[(2-Hydroxyethyl)amino]-3-methylbutanoic acid; (S)-2-((2-Hydroxyethyl)amino)-3-methylbutanoic acid; H-L-Val(2-OH)-OH; N-2-Hydroxyethyl-L-valine; N-(β-Hydroxyethyl)-L-valine; 2-Hydroxyethyl-L-valine
EINECS	Contact for details

Quality Control

Our n-2-(Hydroxyethyl)-L-Valine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.