Description

6-Pyridin-3-Yl-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One CAS NO 101714-48-1 is a high-purity, heterocyclic organic compound featuring a pyrimidinone core substituted with a pyridinyl group and a thioxo moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition and receptor modulation. Industries engaged in pharmaceutical R&D, agrochemical development, and fine chemical synthesis will find this compound essential for their exploratory and process chemistry workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, especially for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Development: Used in research for creating novel pesticides and herbicides, leveraging its heterocyclic bioactivity.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Fine Chemical Synthesis: Acts as a specialized building block for synthesizing complex, high-value organic molecules.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Pyridin-3-Yl-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One
CAS No.	101714-48-1
Molecular Formula	C9H7N3OS
Molecular Weight	205.24 g/mol
Synonyms	6-(Pyridin-3-yl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 6-(3-Pyridinyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 6-(3-Pyridyl)-2-mercapto-4-hydroxypyrimidine; 3-Pyridinyl-6-thioxo-1,6-dihydropyrimidin-4-ol; 101714-48-1; 6-Pyridin-3-yl-2-thioxo-1,2-dihydropyrimidin-4-ol; 6-(3-Pyridyl)-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our production of 6-Pyridin-3-Yl-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized and verified using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.