Description

Argipressin (5-8), (2-1')-Disulfide Cys(6)- is a synthetic cyclic peptide analog of vasopressin, a key hormone involved in water retention and vasoconstriction. This compound is of significant interest for its role in advanced biochemical research and pharmaceutical development, particularly in studying receptor-ligand interactions and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on endocrinology, cardiovascular research, and peptide-based therapeutic discovery.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of vasopressin receptor (V1a, V2) signaling and function.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics for conditions like diabetes insipidus or septic shock.
• Endocrinology Studies: Employed in in vitro and in vivo models to investigate the physiological effects of vasopressin analogs on water balance and blood pressure regulation.
• Peptide Chemistry: Acts as a model compound for studying disulfide bridge formation, peptide stability, and structure-activity relationships (SAR).
• Diagnostic Reagent Manufacturing: May be used in the production of diagnostic kits for assessing renal function and endocrine disorders.

Basic Information

Product Name	Argipressin (5-8), (2-1')-Disulfide Cys(6)-
CAS No.	101531-76-4
Molecular Formula	C46H65N13O12S2
Molecular Weight	1040.2 g/mol
Synonyms	[Cys6]-Argipressin (5-8); Argipressin (5-8) cyclic (2-1')-disulfide with Cys at position 6; Vasopressin (5-8) fragment, cyclic Cys6 analog; Cyclo(Cys-Tyr-Phe-Gln-Asn-Cys)-Pro-Arg-Gly-NH2; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (cyclic 2-1' disulfide); AVP (5-8) cyclic analog
EINECS	Contact for details

Quality Control

Our Argipressin (5-8), (2-1')-Disulfide Cys(6)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.