Description

3-Chloro-2,4,5-Trifluorobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block essential for advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which imparts specific electronic and steric properties crucial for developing active pharmaceutical ingredients and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Cross-Coupling Reactions: Acts as a versatile electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Chloro-2,4,5-Trifluorobenzaldehyde
CAS No.	101513-80-8
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,4,5-Trifluoro-3-chlorobenzaldehyde; 3-Chloro-2,4,5-trifluorobenzenecarboxaldehyde; Benzaldehyde, 3-chloro-2,4,5-trifluoro-; 3-Chloro-2,4,5-trifluoro benzaldehyde; 3-Chloro-2,4,5-trifluorophenyl aldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2,4,5-Trifluorobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.