Description

Conotoxin Giii CAS NO 101484-15-5 is a highly specific and potent peptide neurotoxin derived from the venom of marine cone snails. This compound is of significant value in neuroscience research and pharmaceutical development due to its selective antagonism of neuronal nicotinic acetylcholine receptors (nAChRs). It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on neurological disorders, pain management, and the development of novel therapeutic agents and research tools.

Application

• Neuroscience Research: As a selective pharmacological tool for studying the function and distribution of specific subtypes of neuronal nicotinic acetylcholine receptors (nAChRs).
• Drug Discovery & Development: Serving as a lead compound or molecular template for the design of new analgesics and neuroprotective agents.
• Ion Channel Studies: Used in electrophysiology and binding assays to characterize and differentiate between various ion channel subtypes.
• Biochemical Reagent: Employed in the development of high-specificity assays and diagnostic research kits.
• Academic & Pharmaceutical R&D: Fundamental research into synaptic transmission, neuronal signaling pathways, and the pathophysiology of neurological conditions.

Basic Information

Product Name	Conotoxin Giii
CAS No.	101484-15-5
Molecular Formula	C92H138N30O28S6
Molecular Weight	~2196.6 g/mol
Synonyms	Conotoxin GIII; α-Conotoxin GIII; α-Conotoxin GIII; Conotoxin GI; ω-Conotoxin GIII; SNX-325; μ-Conotoxin GIII; Cone Snail Toxin GIII; MrIA; Contulakin-G
EINECS	Contact for details

Quality Control

Our Conotoxin Giii is produced and tested under stringent quality management protocols to ensure the highest standards of purity and biological activity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and potency. We adhere to relevant guidelines for research-grade biochemicals to guarantee reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Biological Activity	Assayed; specific activity available on COA
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.