Description

H-2-Abu-Tyr-Oh is a chemically synthesized, non-natural amino acid derivative featuring an L-tyrosine backbone modified with an amino butyric acid (Abu) group. This compound is a crucial building block in advanced peptide synthesis and pharmaceutical research, offering a unique structural motif for modulating peptide properties and biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key raw material in the synthesis of novel peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Peptide Synthesis Building Block: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified tyrosine residues, influencing peptide stability, solubility, and receptor binding.
• Biochemical Research: Employed in structure-activity relationship (SAR) studies to investigate the role of specific amino acid modifications on protein function and interaction.
• Diagnostic Agent Development: Acts as a precursor for radiolabeled or fluorescently tagged peptides used in medical imaging and diagnostic assays.
• Cosmeceutical Peptides: A potential ingredient in the synthesis of bioactive peptides for advanced skincare formulations targeting specific skin receptors.

Basic Information

Item	Detail
Product Name	H-2-Abu-Tyr-Oh
CAS No.	101265-94-5
Molecular Formula	C₁₄H₂₀N₂O₅
Molecular Weight	296.32 g/mol
Synonyms	H-Abu-Tyr-OH; N-[(2S)-2-Amino-4-hydroxybutanoyl]-L-tyrosine; 2-Amino-4-hydroxybutyryl-L-tyrosine; Abu-Tyrosine; L-Tyrosine, N-(2-amino-4-hydroxybutanoyl)-; (2S)-2-[(2S)-2-Amino-4-hydroxybutanamido]-3-(4-hydroxyphenyl)propanoic acid; Fmoc-Abu-Tyr-OH (protected form precursor)
EINECS	Contact for details

Quality Control

Our H-2-Abu-Tyr-Oh is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.