Description

8-Bromo-7-(2-Hydroxypropyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, functionalized purine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for the development of novel therapeutic agents, particularly in the fields of oncology and antiviral research. It is essential for research institutions, custom synthesis houses, and pharmaceutical companies engaged in the discovery and production of next-generation active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel xanthine-based drug candidates targeting adenosine receptors.
• Anticancer Agent Research: Used as a precursor in the development of potential chemotherapeutic compounds and kinase inhibitors.
• Antiviral Drug Development: Serves as a core scaffold for creating molecules with potential activity against viral enzymes.
• Biochemical Research: Employed in enzymatic studies and as a probe for investigating purinergic signaling pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom organic synthesis projects and scale-up processes.
• Academic Research: Used in university and institutional labs for methodological development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	8-Bromo-7-(2-Hydroxypropyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	101072-16-6
Molecular Formula	C9H11BrN4O3
Molecular Weight	303.11 g/mol
Synonyms	8-Bromo-7-(2-hydroxypropyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 8-Bromo-7-(2-hydroxypropyl)-3-methylxanthine; 8-Bromo-7-(2-hydroxypropyl)theophylline; 1H-Purine-2,6-dione, 8-bromo-7-(2-hydroxypropyl)-3-methyl-3,7-dihydro-; 8-Bromo-7-(2-hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (tautomer); 8-Bromopentoxifylline derivative; Br-PTX derivative
EINECS	Contact for details

Quality Control

Our 8-Bromo-7-(2-Hydroxypropyl)-3-Methyl-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.