Description

4-Nitro-3-(Trifluoromethyl)Benzaldehyde is a versatile aromatic aldehyde building block characterized by its nitro and trifluoromethyl substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique electronic properties are leveraged. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and non-linear optical (NLO) chromophores.
• Dye and Pigment Intermediate: Acts as a key component in the production of high-performance, light-fast dyes and functional pigments.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects.

Basic Information

Item	Details
Product Name	4-Nitro-3-(Trifluoromethyl)Benzaldehyde
CAS No.	101066-57-3
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	3-(Trifluoromethyl)-4-nitrobenzaldehyde; 4-Nitro-3-trifluoromethylbenzaldehyde; 4-Nitro-α,α,α-trifluoro-m-tolualdehyde; Benzaldehyde, 4-nitro-3-(trifluoromethyl)-; 3-Trifluoromethyl-4-nitrobenzaldehyde; 4-Nitro-α,α,α-trifluoro-3-methylbenzaldehyde; NSC 405124
EINECS	Contact for details

Quality Control

Our 4-Nitro-3-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term storage to maintain purity. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.