Description

2-Fluoro-4-Formyl-Benzonitrile is a versatile aromatic building block featuring both a formyl and a nitrile functional group on a fluorinated benzene ring. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated liquid crystal compounds and electron-transport/hole-blocking materials in organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and dielectric properties for high-performance engineering plastics.
• Chemical Research & Development: Employed in academic and industrial labs for exploring novel organic reactions, catalysis, and as a building block for complex heterocycles.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for niche applications requiring specific light-fastness or color properties.

Basic Information

Product Name	2-Fluoro-4-Formyl-Benzonitrile
CAS No.	101048-76-4
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	4-Cyano-2-fluorobenzaldehyde; 2-Fluoro-4-cyanobenzaldehyde; 4-Formyl-3-fluorobenzonitrile; 3-Fluoro-4-formylbenzonitrile; 2-Fluorobenzaldehyde-4-carbonitrile; 4-Aldehydo-2-fluorobenzonitrile; 2-Fluoro-4-aldehydrobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Formyl-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.