Description

Gly-Arg 4-Methoxy-β-Naphthylamide Dihydrochloride is a specialized chromogenic peptide substrate used as a key reagent in enzymatic assays and biochemical research. Its value lies in its high specificity and sensitivity for detecting protease activity, particularly from enzymes like trypsin and related serine proteases. This compound is essential for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors requiring precise enzyme characterization and inhibitor screening.

Application

• Protease Activity Assays: Primary substrate for the colorimetric detection and quantification of trypsin, thrombin, and other arginine-specific proteases.
• Biochemical Research: Used in kinetic studies, enzyme mechanism elucidation, and the development of new enzymatic detection methods.
• Diagnostic Kit Manufacturing: A critical component in the formulation of diagnostic kits for pancreatic function and other clinical tests measuring protease levels.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) platforms to identify and evaluate novel protease inhibitors as potential drug candidates.
• Quality Control (QC) Testing: Used in QC laboratories to standardize and validate the activity of enzyme preparations and related bioproducts.

Basic Information

Product Name	Gly-Arg 4-Methoxy-β-Naphthylamide Dihydrochloride
CAS No.	100940-56-5
Molecular Formula	C24H32Cl2N6O4
Molecular Weight	531.46 g/mol
Synonyms	Gly-Arg 4-Methoxy-2-Naphthylamide Dihydrochloride; Glycyl-L-arginine 4-methoxy-β-naphthylamide dihydrochloride; G-R 4-Methoxy-β-NA Dihydrochloride; L-Glycyl-L-arginine 4-methoxy-2-naphthylamide dihydrochloride; Trypsin Substrate (4-Methoxy-β-NA); Chromogenic Trypsin Substrate; 4-Methoxy-β-naphthylamide-Gly-Arg dihydrochloride; Bz-Gly-Arg-4MβNA·2HCl
EINECS	Contact for details

Quality Control

Our Gly-Arg 4-Methoxy-β-Naphthylamide Dihydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Solubility	Clear, colorless solution in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.