Description

Phe-Pro-Ala-Met 4-Methoxy-β-Naphthylamide is a specialized fluorogenic peptide substrate designed for the detection and study of specific protease activity. This compound matters for its role as a critical research tool in enzymology and biochemical assay development, offering high sensitivity and specificity. It is primarily needed by researchers and manufacturers in the life sciences sector, particularly for applications in pharmaceutical R&D, diagnostic kit production, and academic biochemical studies.

Application

• Protease Activity Assays: Used as a selective substrate for detecting and quantifying the activity of specific proteolytic enzymes in research settings.
• Enzyme Kinetic Studies: Employed in biochemical research to determine kinetic parameters (Km, Vmax) and inhibition profiles of target proteases.
• High-Throughput Screening (HTS): Utilized in pharmaceutical discovery for screening compound libraries for potential protease inhibitors or activators.
• Diagnostic Development: Serves as a key component in the development of fluorometric diagnostic tests and kits for clinical or research use.
• Cell Biology Research: Applied in studies of intracellular protease function and signaling pathways within live cells or tissue extracts.
• Quality Control in Biomanufacturing: Used to monitor and validate the activity and purity of enzyme preparations in biotechnological production processes.

Basic Information

Product Name	Phe-Pro-Ala-Met 4-Methoxy-β-Naphthylamide
CAS No.	100930-06-1
Molecular Formula	C₃₃H₄₁N₅O₆S
Molecular Weight	635.78 g/mol
Synonyms	L-Phenylalanyl-L-prolyl-L-alanyl-L-methionine 4-methoxy-2-naphthylamide; Phe-Pro-Ala-Met-4-MeO-βNA; Fluorogenic Substrate for Proteases; 4-Methoxy-2-naphthylamide derivative of Phe-Pro-Ala-Met; Protease Substrate 100930-06-1; F-P-A-M-4MβNA
EINECS	Contact for details

Quality Control

Our Phe-Pro-Ala-Met 4-Methoxy-β-Naphthylamide is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.