Description

Methionine Enkephalin-Arg-Phe Acetate Salt is a synthetic peptide analog of the endogenous opioid peptide methionine enkephalin, modified with an Arg-Phe extension. This compound is a valuable research-grade biochemical tool for studying opioid receptor pharmacology, signal transduction, and neurobiological pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, pain management, and peptide-based drug discovery.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, activation, and downstream cellular effects.
• Biochemical Assay Development: Serves as a critical component in the development and validation of high-throughput screening (HTS) assays for novel analgesic targets.
• Signal Transduction Studies: Employed to investigate the intracellular mechanisms and second messenger systems modulated by enkephalin analogs.
• Pharmacological Reference Standard: Provides a benchmark for purity and activity in the quality control of related peptide substances and in vitro experiments.
• Academic & Institutional Research: Supports fundamental research in neurobiology, physiology, and the study of the endogenous opioid system.

Basic Information

Product Name	Methionine Enkephalin-Arg-Phe Acetate Salt
CAS No.	100929-69-9
Molecular Formula	C₃₄H₄₈N₁₀O₈S • xC₂H₄O₂
Molecular Weight	780.90 g/mol (free base)
Synonyms	Met-Enkephalin-Arg-Phe; Tyr-Gly-Gly-Phe-Met-Arg-Phe; Methionine Enkephalin, Arg-Phe extended; Opioid peptide (Met-Enk-Arg-Phe); MEAP; YGGFMRF; H-Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH acetate salt
EINECS	Contact for details

Quality Control

Our research-grade peptides are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	3.0 - 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.