Description

D-Ala-Gly-Phe-Met-NH2 Acetate Salt is a high-purity synthetic peptide derivative, specifically a tetrapeptide amide, offered as its acetate salt form for enhanced stability and solubility. This compound is a critical intermediate and research tool in the development of novel pharmaceutical agents, particularly in the fields of endocrinology and metabolic research. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic research institutions focused on peptide-based drug discovery and biochemical pathway analysis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of more complex peptide hormones and receptor agonists/antagonists.
• Biochemical Assay Development: Used as a standard or substrate in enzymatic studies and receptor binding assays to investigate metabolic pathways.
• Peptide Library Synthesis: A valuable building block for constructing combinatorial peptide libraries for high-throughput screening in drug discovery.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.
• Reference Standard: Functions as a certified reference material (CRM) for quality control and analytical method validation in GMP/GLP environments.

Basic Information

Product Name	D-Ala-Gly-Phe-Met-NH2 Acetate Salt
CAS No.	100929-65-5
Molecular Formula	C22H33N5O5S • xC2H4O2
Molecular Weight	511.60 g/mol (Free base)
Synonyms	D-Ala-Gly-Phe-Met-amide acetate; DAGFM-NH2 Acetate; H-D-Ala-Gly-Phe-Met-NH2 • AcOH; Tetrapeptide Amide Acetate Salt; [D-Alanine1, Glycine2]-Methionine Enkephalin amide acetate; Adrenorphin (4-7) amide acetate; (D-Ala)-Adrenorphin-(4-7)-NH2 acetate
EINECS	Contact for details

Quality Control

Our D-Ala-Gly-Phe-Met-NH2 Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent controls for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert atmosphere (e.g., under argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	1.0 - 3.0 eq
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.