Description

Des-Tyr1-Leucine Enkephalinamide Acetate Salt is a synthetic peptide analog derived from the endogenous opioid peptide enkephalin. This compound is a valuable research tool for studying opioid receptor pharmacology and signal transduction pathways without the confounding effects of the native tyrosine residue. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, pain management, and neuropharmacology.

Application

• Neuroscience Research: Used as a reference compound or antagonist in studies investigating the delta (δ) opioid receptor subtype and its role in pain modulation, mood, and addiction.
• Pharmacological Assay Development: Serves as a critical standard or control in high-throughput screening (HTS) assays designed to discover novel opioid receptor ligands.
• Biochemical Studies: Employed in receptor binding assays, autoradiography, and studies of G-protein coupling to elucidate the structure-activity relationships (SAR) of enkephalin analogs.
• Academic & Clinical Research: Supports fundamental research into the endogenous opioid system, its physiological functions, and potential therapeutic targets for neurological disorders.

Basic Information

Product Name	Des-Tyr1-Leucine Enkephalinamide Acetate Salt
CAS No.	100929-57-5
Molecular Formula	C27H44N6O7 • xC2H4O2
Molecular Weight	564.68 g/mol (free base)
Synonyms	Des-Tyr1-Leu-Enkephalinamide Acetate; H-Leu-Phe-Leu-Phe-NH2 acetate; Leu-Enkephalinamide, Des-Tyr1-; [Leu]Enkephalinamide, 5-desoxy-; DTLEDA; Opioid peptide fragment (4-7); Leu-Phe-Leu-Phe-NH2 acetate salt
EINECS	Contact for details

Quality Control

Our Des-Tyr1-Leucine Enkephalinamide Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC/IC)	As specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.