Description

Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4M-Betana is a synthetic peptide derivative, specifically a modified peptide substrate. This compound is of significant value in biochemical and pharmaceutical research due to its role as a specialized substrate for studying enzyme kinetics and protease activity. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and biotechnology companies engaged in proteomics, drug discovery, and the development of diagnostic assays.

Application

• Protease/Enzyme Substrate: Used as a specific chromogenic or fluorogenic substrate for the study and characterization of various proteolytic enzymes, including matrix metalloproteinases (MMPs) and other serine or cysteine proteases.
• Biochemical Research: Essential tool in enzymatic assays to determine kinetic parameters (Km, Vmax), inhibitor screening, and understanding catalytic mechanisms.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) campaigns to identify and optimize novel therapeutic compounds that modulate protease activity.
• Diagnostic Reagent Component: Can be utilized in the development of in vitro diagnostic kits for detecting specific enzyme activities related to disease states.
• Cell Biology & Signal Transduction Studies: Applied in research investigating proteolytic pathways involved in cellular processes like apoptosis, migration, and inflammation.

Basic Information

Product Name	Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4M-Betana
CAS No.	100900-43-4
Molecular Formula	C58H81N11O13
Molecular Weight	1132.3 g/mol (approx.)
Synonyms	Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4-Methoxy-β-Naphthylamide; Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4M-βNA; Benzyloxycarbonyl-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4-Methoxy-2-Naphthylamide; MMP Substrate; Fluorogenic Peptide Substrate; Protease Substrate 100900-43-4; Chromogenic Peptide Derivative
EINECS	Contact for details

Quality Control

Our Z-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-4M-Betana is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.