Description

β-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Acetate Salt is a high-purity synthetic peptide sequence, also known as a fragment of the angiotensin-converting enzyme (ACE) inhibitor. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in studying cardiovascular regulation and enzyme inhibition mechanisms. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in peptide-based drug discovery and analytical method development.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to the renin-angiotensin system.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of cardiovascular therapeutics.
• Diagnostic Reagents: Employed in the formulation of calibration standards and controls for clinical diagnostic assays measuring ACE activity.
• Peptide Chemistry Studies: Utilized in academic and industrial labs for studying peptide stability, structure-activity relationships (SAR), and analytical method validation.
• Life Science Tools: Incorporated into specialized kits and reagents for cellular and molecular biology research focused on blood pressure regulation pathways.

Basic Information

Product Name	β-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Acetate Salt
CAS No.	100900-31-0
Molecular Formula	C52H78N16O14 • xC2H4O2
Molecular Weight	1151.28 g/mol (Free base)
Synonyms	Angiotensin I (1-9) nonapeptide; Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; DRVYIHPF; ACE Inhibitor Peptide Fragment; H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; β-Aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-prolyl-phenylalanine; Angiotensin I Converting Enzyme Substrate (1-9); [Asp1, Arg2, Val3, Tyr4, Ile5, His6, Pro7, Phe8]-Angiotensin I (1-8) Fragment
EINECS	Contact for details

Quality Control

Our β-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) detailing all specifications to ensure compliance with research and development grade standards. Custom synthesis to meet specific purity requirements (e.g., >95%, >98%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 95.0% (Total Peptide Content)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.