Description

Z-Phe-Arg-4M-Betana Hcl is a specialized fluorogenic peptide substrate designed for the sensitive detection of proteolytic enzyme activity. This compound is critical for biochemical research and diagnostic assay development, offering high specificity and a robust signal-to-noise ratio. It is primarily needed by researchers and manufacturers in the fields of pharmaceutical development, clinical diagnostics, and life science research for studying enzymes like cathepsins and other serine or cysteine proteases.

Application

• Enzyme Activity Assays: As a fluorogenic substrate for kinetic studies and high-throughput screening of protease inhibitors in drug discovery.
• Diagnostic Kit Development: Used in the formulation of diagnostic tests for diseases involving abnormal protease activity, such as cancer and inflammatory conditions.
• Biochemical Research: For the characterization and quantification of specific protease enzymes like cathepsin B, L, and related enzymes in cell lysates and biological fluids.
• Quality Control in Biologics: Monitoring protease activity during the production and purification of therapeutic proteins and antibodies.
• Cell-Based Imaging: Employed in live-cell imaging to visualize and localize protease activity within cellular compartments.
• Academic Research: A key tool in university and institutional labs for fundamental studies in enzymology and proteolysis pathways.

Basic Information

Product Name	Z-Phe-Arg-4M-Betana Hcl
CAS No.	100900-17-2
Molecular Formula	C34H41N7O6 • HCl
Molecular Weight	Contact for details
Synonyms	Z-Phe-Arg-4-Methoxy-β-naphthylamide Hydrochloride; Z-FR-4M-βNA HCl; Benzyloxycarbonyl-Phenylalanyl-Arginyl-4-Methoxy-2-Naphthylamide Hydrochloride; Cathepsin B Substrate (Z-FR-4M-βNA); Fluorogenic Peptide Substrate Z-FR-4M-βNA; Protease Substrate 100900-17-2; Z-FR-4MβNA•HCl
EINECS	Contact for details

Quality Control

Our Z-Phe-Arg-4M-Betana Hcl is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analysis, including HPLC purity verification, identity confirmation (IR, MS), and functional activity testing. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Functional Activity	≥ 95% of reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.