Description

3-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique pyrazolopyrimidine core, functionalized with chloro and methylthio groups, makes it an indispensable intermediate for research and development in pharmaceutical chemistry. This compound is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel compounds for crop protection and pesticide development.
• Chemical Biology Probes: Serves as a scaffold for creating tool compounds to study biological pathways and enzyme functions.
• Material Science: Potential building block for advanced organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for the life sciences industry.

Basic Information

Product Name	3-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	100859-88-9
Molecular Formula	C6H5ClN4S
Molecular Weight	200.65 g/mol
Synonyms	3-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine; 3-Chloro-6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 3-chloro-6-(methylthio)-; 3-Chloro-6-methylmercapto-1H-pyrazolo[3,4-d]pyrimidine; 6-(Methylthio)-3-chloro-1H-pyrazolo[3,4-d]pyrimidine; 3-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine; 100859-88-9
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.