Description

2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-,cis-(9Ci) is a high-purity fluorinated pyrimidinone derivative, a key synthetic intermediate in advanced organic chemistry. This compound is valued for its unique cis-configuration and functional group array, enabling precise molecular construction. It is primarily sought by research institutions and pharmaceutical developers for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, particularly in nucleoside and antiviral research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer drug candidates, leveraging its fluorinated pyrimidine core.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and stability.
• Nucleoside Analog Synthesis: Serves as a precursor for modified nucleosides used in biochemical research and diagnostic applications.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying enzyme mechanisms and cellular processes.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial production of complex molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in medicinal chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-,cis-(9Ci)
CAS No.	100814-57-1
Molecular Formula	C4H6FN3O2
Molecular Weight	147.11 g/mol
Synonyms	cis-4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-2(1H)-pyrimidinone; 4-Amino-5-fluoro-5,6-dihydro-6-hydroxy-2(1H)-pyrimidinone, cis-; 5-Fluoro-5,6-dihydro-6-hydroxy-4-amino-2(1H)-pyrimidinone; 4-Amino-5-fluoro-6-hydroxy-5,6-dihydro-2(1H)-pyrimidinone; 5-Fluoro-6-hydroxy-4-amino-5,6-dihydro-2-pyrimidinone; cis-5-Fluoro-6-hydroxy-4-aminodihydropyrimidin-2-one; 100814-57-1; (cis)-4-Amino-5-fluoro-6-hydroxy-5,6-dihydro-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone,4-Amino-5-Fluoro-5,6-Dihydro-6-Hydroxy-,cis-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.