Description

4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine is a high-purity heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Serves as a core scaffold for developing new active ingredients with potential herbicidal or fungicidal activity.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Intermediate for creating complex, functionalized pyrazolopyrimidine derivatives for various specialty applications.

Basic Information

Product Name	4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine
CAS No.	100644-66-4
Molecular Formula	C7H7ClN5
Molecular Weight	196.62 g/mol
Synonyms	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine; 6-Amino-4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine; 1-Methyl-4-chloro-1H-pyrazolo[3,4-d]pyrimidin-6-amine; 4-Chloro-1-methyl-6-amino-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-1-methylpyrazolo[3,4-d]pyrimidin-6-amine; CAS 100644-66-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.