Description

2-(4-Bromophenyl)Quinazoline-4(3H)-Thione is a high-value brominated quinazoline derivative, a versatile heterocyclic building block prized for its role in advanced organic synthesis. Its core value lies in enabling the development of novel pharmacologically active compounds, particularly in medicinal chemistry research. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active quinazoline-based compounds.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and pesticides that leverage the quinazoline core.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a building block for electron-transport or emissive layer materials in electronic applications.
• Coordination Chemistry & Ligand Synthesis: The thione and nitrogen atoms can act as donors for metal coordination, useful in creating catalysts or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-(4-Bromophenyl)Quinazoline-4(3H)-Thione
CAS No.	100527-50-2
Molecular Formula	C14H9BrN2S
Molecular Weight	317.20 g/mol
Synonyms	4(3H)-Quinazolinethione, 2-(4-bromophenyl)-; 2-(4-Bromophenyl)-4-mercaptoquinazoline; 2-(p-Bromophenyl)-4-quinazolinethiol; 2-(4-Bromophenyl)-3,4-dihydro-4-thioxoquinazoline; 2-(4-Bromophenyl)quinazoline-4-thiol; 2-(4-Bromophenyl)-4-thioxo-3,4-dihydroquinazoline; 4-Thioxo-2-(4-bromophenyl)-3,4-dihydroquinazoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)Quinazoline-4(3H)-Thione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.