Description

Prepro-Thyrotropin-Releasing Hormone is a synthetic peptide precursor of the neurohormone Thyrotropin-Releasing Hormone (TRH). This high-purity compound is critical for advanced biochemical research and pharmaceutical development, particularly in the study of neuroendocrine signaling pathways and hormone biosynthesis. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focusing on endocrinology, neuroscience, and peptide-based therapeutic discovery.

Application

• Biochemical Research: Fundamental studies on the biosynthesis, processing, and regulation of Thyrotropin-Releasing Hormone (TRH).
• Neuroendocrinology Studies: Investigation of hypothalamic-pituitary-thyroid axis function and related disorders.
• Pharmaceutical R&D: Serves as a key reference standard and starting material in the development of diagnostic tools or therapeutic agents targeting TRH pathways.
• Peptide Chemistry: Used as a model compound in methodological development for peptide synthesis, purification, and analysis.
• Cell Signaling Assays: Application in in vitro cellular assays to study receptor interactions and downstream signal transduction mechanisms.

Basic Information

Product Name	Prepro-Thyrotropin-Releasing Hormone
CAS No.	100469-84-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Prepro-TRH; Thyrotropin-Releasing Hormone Precursor; TRH Precursor; Preprothyroliberin; pGlu-His-Pro-Gly-Lys-Arg-Amide Precursor; Pro-TRH; TRH Prohormone; Hypophysiotropic Hormone Precursor
EINECS	Contact for details

Quality Control

Our Prepro-Thyrotropin-Releasing Hormone is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assay by HPLC, identity confirmation, and impurity profiling to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.